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Using powerful computational tools and a variety of databases – from insurance claims files to pharmacy records to real-time emergency-room data – Kenneth Mandl, PhD, MPH and John Brownstein, PhD, have made a variety of discoveries, many of them unexpected, and all of them relevant to public health. Here, they discuss some recent projects and their future plans, comment on the power and limits of bioinformatics and lay forth their goal of taking their technology to the people and capturing …